LY81067
LY81067, a diaryltriazine, effectively protects against Pentylenetetrazole- and Picrotoxin-induced convulsions in mice. LY81067 exerts its anticonvulsant effects by binding to or near Picrotoxin binding sites[1].
Product Specifications
CAS Number
87186-60-5
UNSPSC
12352005
Target
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly81067.html
Solubility
10 mM in DMSO
Smiles
OC1CCN(CC1)C2=NC(C3=CC=C(C=C3)C)=C(N=N2)C4=CC=C(C=C4)C
Molecular Formula
C22H24N4O
Molecular Weight
360.45
References & Citations
[1]D T Wong, et al. Enhanced binding of radioligands to receptors of gamma-aminobutyric acid and benzodiazepine by a new anticonvulsive agent, LY81067. Life Sci. 1983 Sep 5;33 (10) :917-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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