FP0429
FP0429 is a full mGlu4 agonist and partial mGlu8 agonist with EC50 values of 48.3 μM and 56.2 μM, respectively[1].
Product Specifications
CAS Number
[870860-41-6]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fp0429.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@H]1N(C[C@@](N)(C1)C(O)=O)C(/C=C/C(O)=O)=O
Molecular Formula
C10H12N2O7
Molecular Weight
272.21
References & Citations
[1]Schann S, et al. Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids) : identification of a new group III metabotropic glutamate receptor selective agonist. Bioorg Med Chem Lett. 2006 Sep 15;16 (18) :4856-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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