Calpain Inhibitor VI

Calpain Inhibitor VI (SJA6017) is a synthesized peptide aldehyde inhibitor of calpain. Calpain Inhibitor VI inhibits purified m-calpain with the IC50 of 80 nM. Calpain Inhibitor VI can be used for the research of cataract[1].

Product Specifications

CAS Number

[190274-53-4]

Product Name Alternative

SJA6017

UNSPSC

12352005

Target

Proteasome

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/calpain-inhibitor-vi.html

Purity

99.88

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(S(N[C@H](C(N[C@@H](CC(C)C)C=O)=O)C(C)C)(=O)=O)C=C1

Molecular Formula

C17H25FN2O4S

Molecular Weight

372.45

References & Citations

[1]C Fukiage, et al. SJA6017, a newly synthesized peptide aldehyde inhibitor of calpain: amelioration of cataract in cultured rat lenses. Biochim Biophys Acta. 1997 Oct 24;1361 (3) :304-12.