Corifollitropin alfa

Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility[1][2][3].

Product Specifications

CAS Number

[195962-23-3]

Product Name Alternative

Org 36286; MK-8962

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Estrogen Receptor/ERR

Type

Inhibitory Antibodies

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/corifollitropin-alfa.html

Solubility

10 mM in DMSO

Smiles

[Corifollitropinalfa]

Molecular Weight

(25.4 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Loutradis D, et al. Corifollitropin alfa, a long-acting follicle-stimulating hormone agonist for the treatment of infertility. Curr Opin Investig Drugs. 2009 Apr;10 (4) :372-80. |[2]Verbost P, et al. Pharmacologic profiling of corifollitropin alfa, the first developed sustained follicle stimulant. Eur J Pharmacol. 2011 Jan 25;651 (1-3) :227-33. |[3]Viudes-de-Castro MP, et a. A single injection of corifollitropin alfa supplemented with human chorionic gonadotropin increases follicular recruitment and transferable embryos in the rabbit. Reprod Domest Anim. 2019 Apr;54 (4) :696-701.