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NSC-77053

NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].

Product Specifications

CAS Number

77308-57-7

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/nsc-77053.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=CC=C1C(C2=CC3=C(C=C2)C(C=CC=C4)=C4C3)=O)O

Molecular Formula

C21H14O3

Molecular Weight

314.33

References & Citations

[1]Yuchen Zhou, et al. Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity. Bioorg Med Chem. 2016 Oct 15;24 (20) :4875-4889.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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