NSC-77053
NSC-77053 is a potent BoNT/E inhibitor with an IC50 and a Ki of 2.4 μM and 1.29 μM, respectively[1].
Product Specifications
CAS Number
77308-57-7
UNSPSC
12352005
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/nsc-77053.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=CC=C1C(C2=CC3=C(C=C2)C(C=CC=C4)=C4C3)=O)O
Molecular Formula
C21H14O3
Molecular Weight
314.33
References & Citations
[1]Yuchen Zhou, et al. Identification of small molecule inhibitors of botulinum neurotoxin serotype E via footprint similarity. Bioorg Med Chem. 2016 Oct 15;24 (20) :4875-4889.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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