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WF-536

WF-536 is an orally active inhibitor of Rho-associated coiled-coil-containing protein kinase (ROCK) . WF-536 has tumor anti-metastatic activity. WF-536 can be used for the research of cancer[1].

Product Specifications

CAS Number

539857-64-2

UNSPSC

12352005

Target

ROCK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton; Stem Cell/Wnt; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wf-536.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)[C@@H](C)N)NC2=CC=NC=C2.Cl

Molecular Formula

C14H16ClN3O

Molecular Weight

277.75

References & Citations

[1]Nakajima, Masahide et al. Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions. European journal of pharmacology vol. 459,2-3 (2003) : 113-20.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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