12-Oxo phytodienoic acid
12-Oxo phytodienoic acid (12-OPDA) is a plant lipid-derived anti-inflammatory compound. 12-Oxo phytodienoic acid suppresses neuroinflammation by inhibiting Nf-κB and p38 MAPK signaling in Lipopolysaccharides (LPS) (HY-D1056) -activated cells. 12-Oxo phytodienoic acid can be used for neurodegenerative diseases research[1].
Product Specifications
CAS Number
[85551-10-6]
Product Name Alternative
12-OPDA
UNSPSC
12352211
Hazard Statement
H225, H350
Target
NF-κB; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/12-oxo-phytodienoic-acid.html
Concentration
3.42 mM * 100 μL in Ethanol
Purity
99.57
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCCCCC[C@H]1C=CC([C@H]1C/C=C\CC)=O
Molecular Formula
C18H28O3
Molecular Weight
292.41
Precautions
H225, H350
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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