Propargyl-PEG2-NHBoc
Propargyl-PEG2-NHBoc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Propargyl-PEG2-NHBoc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-NHBoc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
869310-84-9
UNSPSC
12352203
Hazard Statement
H302, H312, H332
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg2-nhboc.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
O=C(NCCOCCOCC#C)OC(C)(C)C
Molecular Formula
C12H21NO4
Molecular Weight
243.30
Precautions
H302, H312, H332
References & Citations
[1]Nello Mainolfi, et al. rak degraders and uses thereof. US20190192668A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers; Cleavable Linker; PEG Linkers
Frequently Asked Questions
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