SC-22716
SC-22716 is a potent, competitive, reversible inhibitor of human LTA4 hydrolase, with an IC50 of 0.20 µM. SC-22716 has potential for the research of inflammatory bowel disease (IBD) and psoriasis[1].
Product Specifications
CAS Number
262451-89-8
UNSPSC
12352005
Target
Aminopeptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sc-22716.html
Solubility
10 mM in DMSO
Smiles
N1(CCCC1)CCOC2=CC=C(C=C2)C3=CC=CC=C3
Molecular Formula
C18H21NO
Molecular Weight
267.37
References & Citations
[1]Penning TD, et, al. Structure-activity relationship studies on 1-[2- (4-Phenylphenoxy) ethyl]pyrrolidine (SC-22716), a potent inhibitor of leukotriene A (4) (LTA (4) ) hydrolase. J Med Chem. 2000 Feb 24;43 (4) :721-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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