IK-862
IK-862 is a selective inhibitor of TACE[1].
Product Specifications
CAS Number
478911-60-3
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ik-862.html
Solubility
10 mM in DMSO
Smiles
C[C@]1(C2=CC=C(C=C2)OCC3=CC(C)=NC4=C3C=CC=C4)C(N(CC1)[C@H](C)C(NO)=O)=O
Molecular Formula
C25H27N3O4
Molecular Weight
433.50
References & Citations
[1]Georgiadis D, et al. Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge. Bioorg Med Chem. 2008;16 (19) :8781-8794. doi:10.1016/j.bmc.2008.08.058
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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