JNJ-17156516
JNJ-17156516 is an orally active, potent, and selective cholecystokinin (CCK) 1-receptor antagonist[1].
Product Specifications
CAS Number
649551-06-4
UNSPSC
12352005
Target
Cholecystokinin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jnj-17156516.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](CC1=NN(C(C2=CC=C(C(Cl)=C2)Cl)=C1)C3=CC=C(C=C3)OC)C4=CC=CC(C)=C4)O
Molecular Formula
C26H22Cl2N2O3
Molecular Weight
481.37
References & Citations
[1]Morton MF, et al. 3-[5- (3,4-Dichloro-phenyl) -1- (4-methoxy-phenyl) -1H-pyrazol-3-yl]-2-m-tolyl-propionate (JNJ-17156516), a novel, potent, and selective cholecystokinin 1 receptor antagonist: in vitro and in vivo pharmacological comparison with dexloxiglumide. J Pharmacol Exp Ther. 2007;323 (2) :562-569. IF: 3.5 Q2 B2
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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