Platencin
Product Specifications
UNSPSC Description
Platencin is a natural, broad spectrum Gram-positive antibiotic isolated from S. platensis. Platencin inhibits β-ketoacyl-ACP synthases II and III (FabF and FabH, respectively) with IC50s of 1.95 and 3.91 μg/ml, respectively[1].
Target Antigen
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/platencin.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C[C@]2(CC3)CC([C@@]3(C[C@]2([C@@]1(CCC(NC4=C(C(C(O)=O)=CC=C4O)O)=O)C)[H])[H])=C
Molecular Weight
425.47
References & Citations
[1]Wang J, et al. Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7612-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118512/Platencin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118512/
Clinical Information
No Development Reported
CAS Number
869898-86-2
Curated Selection
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