H-Pro-Glu-OH

H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway[1].

Product Specifications

CAS Number

[67644-00-2]

UNSPSC

12352005

Hazard Statement

H315-H319

Target

Lipase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/h-pro-glu-oh.html

Solubility

10 mM in DMSO

Smiles

O=C(CC[C@H](NC([C@H]1NCCC1)=O)C(O)=O)O

Molecular Formula

C10H16N2O5

Molecular Weight

244.24

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Daleke MH, et al. Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem. 2011 May 27;286 (21) :19024-34.