H-Pro-Glu-OH
H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway[1].
Product Specifications
CAS Number
67644-00-2
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Lipase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/h-pro-glu-oh.html
Solubility
10 mM in DMSO
Smiles
O=C(CC[C@H](NC([C@H]1NCCC1)=O)C(O)=O)O
Molecular Formula
C10H16N2O5
Molecular Weight
244.24
Precautions
P264-P280-P302+P352-P362+P364
References & Citations
[1]Daleke MH, et al. Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem. 2011 May 27;286 (21) :19024-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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