SJ-3366
SJ-3366 (IQP-0410) is a potent inhibitor of HIV nonnucleoside reverse transcriptase[1]. SJ-3366 (IQP-0410) inhibits HIV at sub-nanomolar concentrations primarily through a typical non-nucleoside mechanism[2].
Product Specifications
CAS Number
195720-26-4
Product Name Alternative
IQP-0410
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sj-3366.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(CC)=C(N1CC2CC=CC2)C(C3=CC(C)=CC(C)=C3)=O)=O
Molecular Formula
C21H24N2O3
Molecular Weight
352.43
References & Citations
[1]Ham AS, Lustig W, Yang L, Boczar A, Buckheit KW, Buckheit RW Jr. In vitro and ex vivo evaluations on transdermal delivery of the HIV inhibitor IQP-0410. PLoS One. 2013;8 (9) :e75306.|[2]Buckheit RW Jr, Watson Buckheit K, Sturdevant CB, Buckheit RW 3rd. Selection and characterization of viruses resistant to the dual acting pyrimidinedione entry and non-nucleoside reverse transcriptase inhibitor IQP-0410. Antiviral Res. 2013;100 (2) :382-391.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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