SCH-451659
SCH-451659 is an inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs) for cancer research[1].
Product Specifications
CAS Number
[502628-66-2]
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sch-451659.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)[C@@H]1N(CCN(C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(CC4CCN(CC4)C(C)=O)=O
Molecular Formula
C30H39Cl2N3O2
Molecular Weight
544.56
References & Citations
[1]Joanna M Day, et al. STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model. Endocr Relat Cancer. 2013 Feb 18;20 (1) :53-64.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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