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SCH-451659

SCH-451659 is an inhibitor of 17β-hydroxysteroid dehydrogenases (17β-HSDs) for cancer research[1].

Product Specifications

CAS Number

[502628-66-2]

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sch-451659.html

Solubility

10 mM in DMSO

Smiles

CC(C)(C)[C@@H]1N(CCN(C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(CC4CCN(CC4)C(C)=O)=O

Molecular Formula

C30H39Cl2N3O2

Molecular Weight

544.56

References & Citations

[1]Joanna M Day, et al. STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model. Endocr Relat Cancer. 2013 Feb 18;20 (1) :53-64.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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