LB-205

LB-205 is a pan-histone deacetylase inhibitor (HDACi) . LB-205 can be used for the research of acute traumatic brain injury[1][2].

Product Specifications

CAS Number

[1113025-86-7]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/lb-205.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=CC=C1S)NCCCCCC(NC2=CC=CC=C2)=O

Molecular Formula

C19H22N2O2S

Molecular Weight

342.46

References & Citations

[1]Lu J, et, al. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Jun 25;110 (26) :10747-52. |[2]Lu J, et, al. Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease. Proc Natl Acad Sci U S A. 2011 Dec 27;108 (52) :21200-5.