AC-93253

AC-93253 is a selective, potent SIRT2 inhibitor. AC93253 can inhibit SIRT2 with an IC50 value of 6 μM. AC93253 can be used for the research of tumors[1].

Product Specifications

CAS Number

[108527-83-9]

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ac-93253.html

Purity

99.3

Solubility

10 mM in DMSO

Smiles

CC1(C)C2=C(C=CC=C2)N(C)/C1=C/C=C/C3=[N+](CC)C4=C(C=CC=C4)S3.[I-]

Molecular Formula

C23H25IN2S

Molecular Weight

488.43

References & Citations

[1]Zhang, Yingjia et al. Identification of a small molecule SIRT2 inhibitor with selective tumor cytotoxicity. Biochemical and biophysical research communications vol. 386,4 (2009) : 729-33.