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Kazusamycin B

Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer[1][2].

Product Specifications

CAS Number

107140-30-7

Product Name Alternative

PD 124895; CL-1957E

UNSPSC

12352005

Target

Antibiotic

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/kazusamycin-b.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C(CC(C(C(C(C(/C=C(/C=C/CC(/C=C(/C=C/C1C(C=CC(O1)=O)C)C)C)C)CO)=O)C)O)C)\C)O

Molecular Formula

C32H46O7

Molecular Weight

542.70

References & Citations

[1]Funaishi K, et, al. Kazusamycin B, a novel antitumor antibiotic. J Antibiot (Tokyo) . 1987 Jun;40 (6) :778-85.|[2]Funaishi K, et, al. Kazusamycin B, a novel antitumor antibiotic. J Antibiot (Tokyo) . 1987 Jun;40 (6) :778-85.|[3]Takamiya K, et, al. The effect of kazusamycin B on the cell cycle and morphology of cultured L1210 cells. J Antibiot (Tokyo) . 1988 Dec;41 (12) :1854-61.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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