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PD-307243

PD-307243 is a hERG channel activator. PD-307243 can be used for research of arrhythmias[1].

Product Specifications

CAS Number

[313533-41-4]

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/pd-307243.html

Solubility

10 mM in DMSO

Smiles

O=C(O)C1=CC=CN=C1NC2=CC3=C(C=C2)CN(C3)C4=CC=C(C(Cl)=C4)Cl

Molecular Formula

C20H15Cl2N3O2

Molecular Weight

400.26

References & Citations

[1]Gordon E, et al. 2-[2- (3,4-dichloro-phenyl) -2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels. Mol Pharmacol. 2008 Mar;73 (3) :639-51.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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