T16A (inh) -C01
T16A (inh) -C01 is an inhibitor of TMEM16A (ANO1) . T16A (inh) -C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].
Product Specifications
CAS Number
[171506-87-9]
UNSPSC
12352005
Target
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/t16a-inh-c01.html
Purity
90
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OCC)C1=C(OC2=CC=C(C=C12)O)COC3=CC=CC=C3
Molecular Formula
C18H16O5
Molecular Weight
312.32
References & Citations
[1]Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286 (3) :2365-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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