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T16A (inh) -C01

T16A (inh) -C01 is an inhibitor of TMEM16A (ANO1) . T16A (inh) -C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].

Product Specifications

CAS Number

[171506-87-9]

UNSPSC

12352005

Target

Chloride Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/t16a-inh-c01.html

Purity

90

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(OCC)C1=C(OC2=CC=C(C=C12)O)COC3=CC=CC=C3

Molecular Formula

C18H16O5

Molecular Weight

312.32

References & Citations

[1]Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286 (3) :2365-74.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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