T16A(inh)-C01
Product Specifications
UNSPSC Description
T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].
Target Antigen
Chloride Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/t16a-inh-c01.html
Purity
90
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OCC)C1=C(OC2=CC=C(C=C12)O)COC3=CC=CC=C3
Molecular Weight
312.321
References & Citations
[1]Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286(3):2365-74.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-118170/T16A-inh-C01-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-118170/T16A-inh-C01-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
171506-87-9
Curated Selection
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