Monoethylglycinexylidide

Monoethylglycinexylidide is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver[1].

Product Specifications

CAS Number

[7728-40-7]

UNSPSC

12352005

Hazard Statement

H301

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/monoethylglycinexylidide.html

Solubility

10 mM in DMSO

Smiles

O=C(CNCC)NC1=C(C=CC=C1C)C

Molecular Formula

C12H18N2O

Molecular Weight

206.28

Precautions

P264-P270-P330-P405-P501

References & Citations

[1]Y S Huang, et al. Measuring lidocaine metabolite--monoethylglycinexylidide as a quantitative index of hepatic function in adults with chronic hepatitis and cirrhosis. J Hepatol. 1993 Aug;19 (1) :140-7.