(Rac) -BI 703704
(Rac) -BI 703704 is a potent soluble guanylyl cyclase (sGC) activator. (Rac) -BI 703704 reduces progression of renal damage in the ZSF1 rat, and highlight the potential of sGC activation as an effective therapy for diabetic nephropathy[1].
Product Specifications
CAS Number
1423067-48-4
UNSPSC
12352005
Target
Guanylate Cyclase
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/rac-bi-703704.html
Solubility
10 mM in DMSO
Smiles
O=C(C1C2CN(C3=NC(C4=CC(C)=CC=C4OCC5=CC=C(C(N6CCCCC6)=O)C=C5C)=CS3)CC1CC2)O
Molecular Formula
C32H37N3O4S
Molecular Weight
559.72
References & Citations
[1]Yu L, et al. Picrocrocin exhibits growth inhibitory effects against SKMEL- 2 human malignant melanoma cells by targeting JAK/ STAT5 signaling pathway, cell cycle arrest and mitochondrial mediated apoptosis. J BUON. 2018 Jul-Aug;23 (4) :1163-1168.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7054949 Inquire
Recombinant Rat Glucagon-like peptide 2 receptor (Glp2r), partial
Sign In for Pricing
View Details 
353846-01 48 Tests
Alpha 1 Acid Glycoprotein 1 (ORM1) BioAssayTM ELISA Kit (Human) discontinued
Sign In for Pricing
View Details 353846-02 96 Tests
Alpha 1 Acid Glycoprotein 1 (ORM1) BioAssayTM ELISA Kit (Human) discontinued
Sign In for Pricing
View Details 822754 1 Card (1 Panel (s) x 1 Pack)
STFR P007-297x420-PE-CRD/1 Prohibited Activity Signs & Labels (Adhesive)
Sign In for Pricing
View Details 