L-703014

L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].

Product Specifications

CAS Number

[142638-79-7]

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/l-703014.html

Solubility

10 mM in DMSO

Smiles

O=C(C[C@@H](CCC1=CNC2=C1C=CC=C2)NC(CNC(CCCC3CCNCC3)=O)=O)O

Molecular Formula

C24H34N4O4

Molecular Weight

442.55

References & Citations

[1]J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11 (3) :426-31.|[2]R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43 (19) :3453-73.