L-703014
L-703014 is a fibrinogen receptor antagonist, with the IC50 of 94 nM, that acts as a novel parenteral and potential oral antithrombotic agent[1][2].
Product Specifications
CAS Number
142638-79-7
UNSPSC
12352005
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l-703014.html
Solubility
10 mM in DMSO
Smiles
O=C(C[C@@H](CCC1=CNC2=C1C=CC=C2)NC(CNC(CCCC3CCNCC3)=O)=O)O
Molecular Formula
C24H34N4O4
Molecular Weight
442.55
References & Citations
[1]J S Barrett, et al. Pharmacokinetics and Pharmacodynamics of L-703,014, a Potent Fibrinogen Receptor Antagonist, After Intravenous and Oral Administration in the Dog. Pharm Res. 1994 Mar;11 (3) :426-31.|[2]R M Scarborough, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43 (19) :3453-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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