MHY908
Product Specifications
UNSPSC Description
MHY908 is a potent dual agonist of PPARα and PPARγ[1]. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity[2].
Target Antigen
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mhy908.html
Solubility
10 mM in DMSO
Smiles
CC(OC1=CC=C(C=C1)C2=NC3=CC(Cl)=CC=C3S2)(C(O)=O)C
Molecular Weight
347.82
References & Citations
[1]Park MH, et al. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice. PLoS One. 2013 Nov 14;8(11):e78815. |[2]Park MH, et al. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch Pharm Res. 2015 Apr;38(4):505-11.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117761/MHY908-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117761/
Clinical Information
No Development Reported
CAS Number
1393371-39-5
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