Laurotetanine

Laurotetanine ((+) -Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways[1].

Product Specifications

CAS Number

[128-76-7]

Product Name Alternative

(+) -Laurotetanine

UNSPSC

12352005

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/laurotetanine.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C=C2C3=C4C(CCN[C@]4(CC2=C1)[H])=CC(OC)=C3OC)OC

Molecular Formula

C19H21NO4

Molecular Weight

327.37

References & Citations

[1]Xin XX, et, al. Anti-asthmatic effect of laurotetanine extracted from Litsea cubeba (Lour.) Pers. root on ovalbumin-induced allergic asthma rats, and elucidation of its mechanism of action. TROP J PHARM RES. 2019:18 (6) .