LY3027788 (hydrochloride)
LY3027788 hydrochloride, a diester analog of LY3020371 which is an mGlu2/3 receptor antagonist, is a potent and orally active prodrug of LY3020371. LY3027788 hydrochloride has antidepressant efficacy[1][2].
Product Specifications
CAS Number
[1377615-55-8]
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly3027788-hydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@]1(N)[C@]2([H])[C@@H](C(OCOC(OC(C)C)=O)=O)[C@]2([H])[C@H](O)[C@H]1CSC3=CC=C(F)C(F)=C3)OCOC(OC(C)C)=O.[H]Cl
Molecular Formula
C25H32ClF2NO11S
Molecular Weight
628.04
References & Citations
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117606A/LY3027788-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117606A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR2; mGluR3
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