Caylin-2
Caylin-2, a Nutlin-3 analog, is a MDM2 inhibitor. Caylin-2 can bind to Bcl-XL[1].
Product Specifications
CAS Number
[1392830-09-9]
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caylin-2.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
O=C(N1CC(NCC1)=O)N2[C@@H](C3=CC=C(C=C3)C(F)(F)F)[C@@H](C4=CC=C(C=C4)C(F)(F)F)N=C2C5=C(C=C(C=C5)OC)OC(C)C
Molecular Formula
C32H30F6N4O4
Molecular Weight
648.60
References & Citations
[1]Shin JS, et al. Structural insights into the dual-targeting mechanism of Nutlin-3. Biochem Biophys Res Commun. 2012 Mar 30;420 (1) :48-53.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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