CAY10621

CAY10621 (SKI 5C; compound 5c) is a specific sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 3.3 μM. CAY10621 is low toxic toward cells. CAY10621 has the potential for resistant cancer tumors research[1].

Product Specifications

CAS Number

[120005-55-2]

Product Name Alternative

SKI 5C

UNSPSC

12352005

Hazard Statement

H225, H319, H336

Target

SphK

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cay10621.html

Concentration

22.95 mM * 100 μL in Methyl acetate

Purity

99.3

Solubility

10 mM in DMSO

Smiles

O=C(N1C(C)(C)OC[C@H]1C(C#CCCCCCCCCCCCCC)=O)OC(C)(C)C

Molecular Formula

C26H45NO4

Molecular Weight

435.64

Precautions

H225, H319, H336

References & Citations

[1]Lingkai Wong, et al. Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. J Med Chem. 2009 Jun 25;52 (12) :3618-26.