A-FABP-IN-1

A-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production[1].

Product Specifications

CAS Number

[1310361-52-4]

UNSPSC

12352005

Target

FABP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/a-fabp-in-1.html

Solubility

10 mM in DMSO

Smiles

CC(OC1=CC(C2=CC=CC=C2C3=NN(C(C4=CC=CS4)=C3)C5=CC=C(C=C5)Cl)=CC=C1)(C(O)=O)C

Molecular Formula

C29H23ClN2O3S

Molecular Weight

515.02

References & Citations

[1]Liu X, et al. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg Med Chem Lett. 2011 May 15;21 (10) :2949-52.