A-FABP-IN-1
A-FABP-IN-1 (Compound 5g) is a potent and selective human adipocyte fatty acid-binding protein (a-FABP) inhibitor with a Ki below 1.0 nM. a-FABP-IN-1 inhibits the pro-inflammatory cytokine production[1].
Product Specifications
CAS Number
1310361-52-4
UNSPSC
12352005
Target
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/a-fabp-in-1.html
Solubility
10 mM in DMSO
Smiles
CC(OC1=CC(C2=CC=CC=C2C3=NN(C(C4=CC=CS4)=C3)C5=CC=C(C=C5)Cl)=CC=C1)(C(O)=O)C
Molecular Formula
C29H23ClN2O3S
Molecular Weight
515.02
References & Citations
[1]Liu X, et al. New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein. Bioorg Med Chem Lett. 2011 May 15;21 (10) :2949-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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