WAY-123398
WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].
Product Specifications
CAS Number
138490-53-6
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/way-123398.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C=C1)NS(=O)(C)=O)(N(CCN(C2=NC3=CC=CC=C3N2C)C)C)=O
Molecular Formula
C19H25N5O4S2
Molecular Weight
451.56
References & Citations
[1]Spinelli W, et al. Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes. Cardiovasc Res. 1993 Sep;27 (9) :1580-91.|[2]Spinelli W, et al. Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol. 1992 Dec;20 (6) :913-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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