SL-25.1188

SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].

Product Specifications

CAS Number

[185835-97-6]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sl-25-1188.html

Solubility

10 mM in DMSO

Smiles

O=C1O[C@@H](CN1C2=NOC3=C2C=CC(OCCCC(F)(F)F)=C3)COC

Molecular Formula

C16H17F3N2O5

Molecular Weight

374.31

References & Citations

[1]Saba W, et, al. [ (11) C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64 (1) :61-9.