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SL-25.1188

Product Specifications

UNSPSC Description

SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].

Target Antigen

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sl-25-1188.html

Solubility

10 mM in DMSO

Smiles

O=C1O[C@@H](CN1C2=NOC3=C2C=CC(OCCCC(F)(F)F)=C3)COC

Molecular Weight

374.31

References & Citations

[1]Saba W, et, al. [(11)C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64(1):61-9.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-117502/SL-25-1188-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-117502/

Clinical Information

Phase 1

CAS Number

185835-97-6

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