SL-25.1188
SL-25.1188 is a potent monoamine oxidase B (MAO-B) inhibitor with Ki values of 2.9 and 8.5 nM for human MAO-B and rat MAO-B, respectively. SL-25.1188 can be used for positron emission tomography[1].
Product Specifications
CAS Number
[185835-97-6]
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sl-25-1188.html
Solubility
10 mM in DMSO
Smiles
O=C1O[C@@H](CN1C2=NOC3=C2C=CC(OCCCC(F)(F)F)=C3)COC
Molecular Formula
C16H17F3N2O5
Molecular Weight
374.31
References & Citations
[1]Saba W, et, al. [ (11) C]SL25.1188, a new reversible radioligand to study the monoamine oxidase type B with PET: preclinical characterisation in nonhuman primate. Synapse. 2010 Jan;64 (1) :61-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
MAO-B
Curated Selection
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