CL67
CL67 is a potent hypoxia-inducible factor (HIF) pathway inhibitor. CL67 interferes G-quadruplex structures within promoter sequences. CL67 can be used in research of renal cancer[1].
Product Specifications
CAS Number
1401242-86-1
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cl67.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC(N2N=NC(C3=CC=C4C=CC(C5=CN(C6=CC(NC(CN(CC)CC)=O)=CC=C6)N=N5)=CC4=C3)=C2)=C1)CN(CC)CC
Molecular Formula
C38H42N10O2
Molecular Weight
670.81
References & Citations
[1]Sarah JW, et, al. CL67: A novel G-quadruplex stabilising agent inhibits the HIF-1 pathway. Cancer Res (2011) 71 (8_Supplement) :4506.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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