CAY10410
CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes[1].
Product Specifications
CAS Number
596104-94-8
Product Name Alternative
11-Oxo-prosta-5Z,12E,14Z-trien-1-oic acid
UNSPSC
12352211
Hazard Statement
H225, H319, H336
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cay10410.html
Solubility
10 mM in DMSO
Smiles
O=C1/C([C@H](CC1)C/C=C\CCCC(O)=O)=C/C=C\CCCCC
Molecular Formula
C20H30O3
Molecular Weight
318.45
Precautions
H225, H319, H336
References & Citations
[1]Ray DM, et, al. The peroxisome proliferator-activated receptor gamma (PPARgamma) ligands 15-deoxy-Delta12,14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. J Immunol. 2006 Oct 15;177 (8) :5068-76.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ
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