Fumitremorgin B
Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL[1][2][3].
Product Specifications
CAS Number
[12626-17-4]
UNSPSC
12352005
Target
Endogenous Metabolite; Fungal
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fumitremorgin-b.html
Purity
90.0
Solubility
10 mM in DMSO
Smiles
O=C([C@]1(O)[C@@H](O)C2=C([C@H](/C=C(C)\C)N13)N(C/C=C(C)\C)C4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O
Molecular Formula
C27H33N3O5
Molecular Weight
479.57
References & Citations
[1]Li SM, et, al. Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes. J Antibiot (Tokyo) . 2011 Jan;64 (1) :45-9.|[2]Wang Y, et, al. 2,5-diketopiperazines from the marine-derived fungus Aspergillus fumigatus YK-7. Chem Biodivers. 2012 Feb;9 (2) :385-93.|[3]Li XJ, et, al. Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. J Agric Food Chem. 2012 Apr 4;60 (13) :3424-31.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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