Fumitremorgin B

Fumitremorgin B is a tremorgenic mycotoxin. Fumitremorgin B exhibits significant antifungal activities, with MICs of 6.25-50 μg/mL[1][2][3].

Product Specifications

CAS Number

[12626-17-4]

UNSPSC

12352005

Target

Endogenous Metabolite; Fungal

Type

Natural Products

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fumitremorgin-b.html

Purity

90.0

Solubility

10 mM in DMSO

Smiles

O=C([C@]1(O)[C@@H](O)C2=C([C@H](/C=C(C)\C)N13)N(C/C=C(C)\C)C4=C2C=CC(OC)=C4)N5[C@](CCC5)([H])C3=O

Molecular Formula

C27H33N3O5

Molecular Weight

479.57

References & Citations

[1]Li SM, et, al. Genome mining and biosynthesis of fumitremorgin-type alkaloids in ascomycetes. J Antibiot (Tokyo) . 2011 Jan;64 (1) :45-9.|[2]Wang Y, et, al. 2,5-diketopiperazines from the marine-derived fungus Aspergillus fumigatus YK-7. Chem Biodivers. 2012 Feb;9 (2) :385-93.|[3]Li XJ, et, al. Metabolites from Aspergillus fumigatus, an endophytic fungus associated with Melia azedarach, and their antifungal, antifeedant, and toxic activities. J Agric Food Chem. 2012 Apr 4;60 (13) :3424-31.