Meclofenamic acid
Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m (6) A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively[1][2][3][4].
Product Specifications
CAS Number
644-62-2
Product Name Alternative
Meclofenamate
UNSPSC
12352005
Hazard Statement
H301
Target
Endogenous Metabolite; Fat Mass and Obesity-associated Protein (FTO) ; Gap Junction Protein; Potassium Channel
Type
Reference compound
Related Pathways
Cytoskeleton; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/meclofenamic-acid.html
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic) |Methanol : 7.14 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=CC=C1NC2=C(Cl)C=CC(C)=C2Cl
Molecular Formula
C14H11Cl2NO2
Molecular Weight
296.15
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
