Coformycin
Coformycin, a nucleoside antibiotic, is a potent inhibitor of adenosine deaminase (ADA) from Streptomyces species. Coformycin possesses anti-tumor and anti-bacterial activity[1][2].
Product Specifications
CAS Number
11033-22-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adenosine Deaminase; Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/coformycin.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1C2=C(NC=NC1)N(C=N2)[C@H]3[C@H](O)[C@H](O)[C@H](O3)CO
Molecular Formula
C11H16N4O5
Molecular Weight
284.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Coformycin.|[2]Lukey T, et al. S-adenosylhomocysteine hydrolase activity, deoxyadenosine triphosphate accumulation, and competence of thymocyte and spleen leucocyte response to mitogens in coformycin-treated mice. Biochem Pharmacol. 1983 Apr 15;32 (8) :1399-406.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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