SR-3737
SR-3737 is a JNK3 and p38 inhibitor (IC50: 12 and 3 nM) [1].
Product Specifications
CAS Number
1164153-37-0
UNSPSC
12352005
Target
JNK; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sr-3737.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(OC)=C(OC)C(OC)=C1)C2=CC=CC(N3N=CC4=C3C=CC(NC5=CC=CC=C5F)=C4)=C2
Molecular Formula
C29H25FN4O4
Molecular Weight
512.53
References & Citations
[1]Kamenecka T, et al. Structure-activity relationships and X-ray structures describing the selectivity of aminopyrazole inhibitors for c-Jun N-terminal kinase 3 (JNK3) over p38. J Biol Chem. 2009 May 8;284 (19) :12853-61.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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