SB-206606

SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors[1].

Product Specifications

CAS Number

[116049-78-6]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sb-206606.html

Solubility

10 mM in DMSO

Smiles

O=C(COC1=CC=C(C=C1)C[C@@H](C)NC[C@H](O)C2=CC=CC(Cl)=C2)O

Molecular Formula

C19H22ClNO4

Molecular Weight

363.84

References & Citations

[1]Muzzin P, et al. Characterization of a new, highly specific, beta 3-adrenergic receptor radioligand, [3H]SB 206606. Mol Pharmacol. 1994 Aug;46 (2) :357-63. PMID: 8078497.