What is the catalog number for GSK 690?

The catalog number for GSK 690 is HY-117226.

What sizes are available for GSK 690?

GSK 690 is available in the following size(s): 1 Each.

GSK 690 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GSK 690?

GSK 690 is manufactured by QuantiMol.

What is the estimated delivery time for GSK 690?

Estimated delivery time for GSK 690 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for GSK 690?

The safety data sheet for GSK 690 is available here: http://file.medchemexpress.com/batch_PDF/HY-117226/.

GSK 690

GSK 690 is a reversible inhibitor of lysine specific demethylase 1 (LSD1), with a Kd value of 9 nM and a biochemical IC50 of 37 nM.

Product Specifications

CAS Number

2101305-84-2

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gsk-690.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC=C(C2=CC(OC[C@H]3CNCC3)=CN=C2C4=CC=C(C)C=C4)C=C1

Molecular Formula

C24H23N3O

Molecular Weight

369.46

References & Citations

[1]Mould DP, et al. Development of (4-Cyanophenyl) glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1. J Med Chem. 2017 Oct 12;60 (19) :7984-7999.|[2]Haydn T, et al. Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells. Cell Death Dis. 2017 Jun 15;8 (6) :e2879.