MSX-2
MSX-2 is A2A adenosine receptor antagonist, with Ki of 5 nM in human that plays an important role in Parkinson's disease[1][2].
Product Specifications
CAS Number
[261717-18-4]
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/msx-2.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1=C(C2=O)N(C(/C=C/C3=CC=CC(OC)=C3)=N1)C)CCCO)N2CC#C
Molecular Formula
C21H22N4O4
Molecular Weight
394.42
References & Citations
[1]Manuel de Lera Ruiz, et al. Adenosine A2A Receptor as a Drug Discovery Target. J Med Chem. 2014 May 8;57 (9) :3623-50.|[2]Tina Becic, et al. Growth factors FGF8 and FGF2 and their receptor FGFR1, transcriptional factors Msx-1 and MSX-2, and apoptotic factors p19 and RIP5 participate in the early human limb development. Acta Histochem. 2018 Apr;120 (3) :205-214.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-117184/MSX-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-117184/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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