KB-141
KB-141 is a potent and selective TRβ agonist. The IC50 values are 23.9 nM and 3.3 nM for binding affinities from displacement of T3 from hTRα1 and hTRβ1, respectively. KB-141 has anti-obesity, anti-diabetic, and lipid-lowering effects and can be used as an anti-cholesteremic agent in vivo[1][2].
Product Specifications
CAS Number
[219691-94-8]
UNSPSC
12352005
Target
Thyroid Hormone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kb-141.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=CC(Cl)=C(C(Cl)=C1)OC2=CC=C(C(C(C)C)=C2)O)O
Molecular Formula
C17H16Cl2O4
Molecular Weight
355.21
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6282875-01 0.2 mL
CD1C, CT (CD1C, T-cell surface glycoprotein CD1c, CD1c) (FITC)
Ask
View Details 
MBS6282875-02 5x 0.2 mL
CD1C, CT (CD1C, T-cell surface glycoprotein CD1c, CD1c) (FITC)
Ask
View Details 