AC-90179

AC-90179 is a selective 5-HT2A receptor inverse agonist (Ki = 2.1 nM) and 5-HT2C antagonist, a potential antipsychotic compound[1].

Product Specifications

CAS Number

[359878-19-6]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ac-90179.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC1=CC=C(C)C=C1)C2CCN(C)CC2)CC3=CC=C(OC)C=C3.Cl

Molecular Formula

C23H31ClN2O2

Molecular Weight

402.96

References & Citations

[1]Kimberly E. Vanover, et al. Pharmacological Characterization of AC-90179 [2- (4-Methoxyphenyl) -N- (4-methyl-benzyl) -N- (1-methyl-piperidin-4-yl) -acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist. Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951