TMB-8
TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores.
Product Specifications
CAS Number
[53464-72-5]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tmb-8.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C(OC)=CC(C(OCCCCCCCCN(CC)CC)=O)=C1)OC.Cl
Molecular Formula
C22H38ClNO5
Molecular Weight
431.99
References & Citations
[1]Malagodi MH, et al. Pharmacological evaluation of a new Ca2+ antagonist, 8- (N, N-diethylamino) -octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8) : studies in smooth muscles. Eur J Pharmacol. 1974 Jun;27 (1) :25-33.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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