TMB-8

TMB-8 is a novel Ca 2+ antagonist. TMB-8 may exert inhibitory effects in smooth muscle by blocking Ca 2+ release from intracellular bound stores.

Product Specifications

CAS Number

[53464-72-5]

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tmb-8.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C(OC)=CC(C(OCCCCCCCCN(CC)CC)=O)=C1)OC.Cl

Molecular Formula

C22H38ClNO5

Molecular Weight

431.99

References & Citations

[1]Malagodi MH, et al. Pharmacological evaluation of a new Ca2+ antagonist, 8- (N, N-diethylamino) -octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8) : studies in smooth muscles. Eur J Pharmacol. 1974 Jun;27 (1) :25-33.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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