Inz-1
Product Specifications
UNSPSC Description
Inz-1 is a potent and selective mitochondrial cytochrome bc1 inhibitor for yeast (IC50=8.092 μM) over humans (IC50=45.320 μM). Inz-1 reverses Fluconazole (HY-B0101) or other triazole antifungals’ resistance in?the pathogenic fungus Candida albicans[1].
Target Antigen
Cytochrome P450; Fungal
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/inz-1.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)CN1N=C(C2=CC=CC=C2)C3=C1C=CC=C3
Molecular Weight
266.29
References & Citations
[1]Benjamin M Vincent, et al. A Fungal-Selective Cytochrome Bc 1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance.Cell Chem Biol. 2016 Aug 18;23(8):978-991.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116686/Inz-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116686/
Clinical Information
No Development Reported
CAS Number
897776-15-7
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
