GKA-71
GKA-71 is an orally active Glucokinase activator, possesses an islet protective effect[1].
Product Specifications
CAS Number
[863504-35-2]
UNSPSC
12352005
Target
Glucokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gka-71.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3
Molecular Formula
C21H23N3O6S2
Molecular Weight
477.55
References & Citations
[1]Maria Sörhede Winzell, et al. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice. Eur J Pharmacol. 2011 Aug 1;663 (1-3) :80-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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