GKA-71
Product Specifications
UNSPSC Description
GKA-71 is an orally active Glucokinase activator, possesses an islet protective effect[1].
Target Antigen
Glucokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/gka-71.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3
Molecular Weight
477.55
References & Citations
[1]Maria Sörhede Winzell, et al. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice. Eur J Pharmacol. 2011 Aug 1;663(1-3):80-6.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116682/GKA-71-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116682/
Clinical Information
No Development Reported
CAS Number
863504-35-2
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