GKA-71

GKA-71 is an orally active Glucokinase activator, possesses an islet protective effect[1].

Product Specifications

CAS Number

[863504-35-2]

UNSPSC

12352005

Target

Glucokinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/gka-71.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC(OC2=CC=C(C=C2)S(=O)(C)=O)=CC(O[C@H](COC)C)=C1)NC3=NC(C)=NS3

Molecular Formula

C21H23N3O6S2

Molecular Weight

477.55

References & Citations

[1]Maria Sörhede Winzell, et al. Chronic glucokinase activation reduces glycaemia and improves glucose tolerance in high-fat diet fed mice. Eur J Pharmacol. 2011 Aug 1;663 (1-3) :80-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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