Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

α5IA

α5IA (L-822179) is a selective α5 GABAA receptor inverse agonist with neuroprotective potential[1].

Product Specifications

CAS Number

[215874-86-5]

Product Name Alternative

L-822179

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/α5ia.html

Purity

97.33

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CN1N=NC(COC(C2=C3C=CC=C2)=NN4C3=NN=C4C5=NOC(C)=C5)=C1

Molecular Formula

C17H14N8O2

Molecular Weight

362.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Chitra Vinnakota, et al. An 5 GABAA Receptor Inverse Agonist, 5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures. Int J Mol Sci. 2020 May 6;21 (9) :3284. |[2]Arnaud Duchon, et al. Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABAA inverse agonist. Br J Pharmacol. 2020 Mar;177 (5) :1106-1118.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-116622/α5IA-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-116622/α5IA-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human Interleukin 9 (IL9) ELISA Kit
DL-IL9-Hu-01 48 Tests

Human Interleukin 9 (IL9) ELISA Kit

Ask
View Details
Human Interleukin 9 (IL9) ELISA Kit
DL-IL9-Hu-02 96 Tests

Human Interleukin 9 (IL9) ELISA Kit

Ask
View Details
S 12024-2
MBS5774493 Inquire

S 12024-2

Ask
View Details
Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT
E6409Hu-01 48 Well

Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT

Ask
View Details
Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT
E6409Hu-02 96 Well

Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT

Ask
View Details
Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT
E6409Hu-03 5x 96 Tests

Human WNT1-inducible-signaling pathway protein 3, WISP3 ELISA KIT

Ask
View Details